Chronic Anterior Thalamus Stimulation for Intractable Epilepsy
نویسندگان
چکیده
منابع مشابه
Long-term anterior thalamus stimulation for intractable epilepsy.
BACKGROUND Deep brain stimulation (DBS) has re-emerged as an alternative therapy for intractable epilepsy. In this study, we investigated the feasibility, efficacy and safety of long-term anterior thalamic nucleus (ATN) stimulation for intractable epilepsy. METHODS In this open-label pilot study of electrical stimulation of the ATN, we investigated four cases of intractable epilepsy (one man ...
متن کاملElectrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy.
PURPOSE Animal studies and sporadic case reports in human subjects have suggested that intermittent electrical stimulation of the anterior nucleus of the thalamus reduces seizure activity. We embarked on an open-label pilot study to determine initial safety and tolerability of bilateral stimulation of the anterior nucleus of the thalamus (ANT), to determine a range of appropriate stimulation pa...
متن کاملElectrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy.
PURPOSE We report a multicenter, double-blind, randomized trial of bilateral stimulation of the anterior nuclei of the thalamus for localization-related epilepsy. METHODS Participants were adults with medically refractory partial seizures, including secondarily generalized seizures. Half received stimulation and half no stimulation during a 3-month blinded phase; then all received unblinded s...
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Spinal cord stimulation (SCS) is minimally invasive and reversible therapy for treatment of severe, otherwise nonresponsive chronic pain. Such approach is relatively safe, with very few side-effects, not addictive, and provides enduring therapeutic response. A number of clinical studies support the efficacy of spinal cord stimulation in treating failed back surgery syndrome and complex regional...
متن کاملEchinoderm microtubule-associated protein -like protein 5 in anterior temporal neocortex of patients with intractable epilepsy
Objective(s):EMAP-like Protein 5 (EML5) is a new echinoderm microtubule-associated protein that is expressed in the central nervous system. The aim of this study was to investigate the expression profile of EML5 in the anterior temporal neocortex of patients presenting with intractable epilepsy (IE). Materials and Methods:Western blot assays were performed to determine EML5 expression in 36 su...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2002
ISSN: 0013-9580,1528-1167
DOI: 10.1046/j.1528-1157.2002.26001.x